For my children's game we were updating the setting to modern setting with magic and monsters and I'm tweaking the foci for it.
Here is my first shot:
Communication: Animal Handling, Bargaining, Deception, Disguise, Etiquette, Gambling, Investigation, Leadership, Performance, Persuasion, Seduction.
Constitution: Drinking, Running, Stamina, Swimming.
Cunning: Arcane Studies, Computers, Cryptid Studies, Cultural Studies, Electronics, Engineering, Evaluation, Healing, Historical Studies, Military Studies, Religious Studies, Research, Science.
Dexterity: Acrobatics, Bows, Brawling, Crafting, Grenades, Guns, Initiative, Legerdemain, Light Blades, Lock Picking, Riding, Staves, Stealth, Traps.
Magic: Arcane Lance, Blood, Creation, Entropy, Primal, Spirit.
Perception: Empathy, Hearing, Mechanical Repair, Searching, Seeing, Smelling, Tracking.
Strength: Axes, Bludgeons, Climbing, Driving, Heavy Blades, Intimidation, Jumping, Might, Spears.
Willpower: Courage, Faith, Morale, Self-Discipline.